PrPCWD in rectal lymphoid tissue of deer (Odocoileus spp.)

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Patterns of PrPCWD accumulation during the course of chronic wasting disease infection in orally inoculated mule deer (Odocoileus hemionus).

Patterns of abnormal prion protein (PrP) accumulation during the course of chronic wasting disease (CWD) infection were studied and the distribution and timing of disease-associated PrP (PrP(CWD)) deposition and lesions in 19 mule deer (Odocoileus hemionus) 90-785 days after oral inoculation were described. PrP(CWD) deposition occurred relatively rapidly and widely in lymphoid tissues, later in...

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ژورنال

عنوان ژورنال: Journal of General Virology

سال: 2007

ISSN: 0022-1317,1465-2099

DOI: 10.1099/vir.0.82342-0